Non Clinical

Non-clinical studies are also known as Pre-Clinical research studies that are conducted, typically on animals, before a permit for a clinical examination on humans can be obtained. Pre-clinical research studies work a significant role in the growth processes and drug discovery and. This research work can be used to examine lead compounds probable to possess constructive pharmacokinetic and biopharmaceutical properties in humans. In adding, they can make easy transition of discovery to progress, as well as lessen the requirement for costly and prolonged clinical studies. Non Clinical research studies include a broad range of studies in a variety of systems to characterize pharmacokinetic and biopharmaceutical properties. Systems used include: in isolated perfused liver, vivo animal models, intestine, kidney, hind limb and heart, Caco-2 cell monolayer absorption model, animal and human liver microsomes (A tiny grain).